Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24457962 | 0.86 | PRMT5 (0.50) | PRMT5EGFRCYP2D6HSD11B1HCAR1 | |
| SCHEMBL24457922 | 0.86 | PRMT5 (0.50) | PRMT5EGFRCYP2D6HSD11B1HCAR1 | |
| SCHEMBL23408954 | 0.86 | PRMT5 (0.50) | PRMT5EGFRCYP2D6HSD11B1HCAR1 | |
| SCHEMBL27020005 | 0.83 | PRMT5 (0.44) | PRMT5EGFRCYP2D6HSD11B1HCAR1 | |
| SCHEMBL25069062 | 0.83 | PRMT5 (0.44) | PRMT5EGFRCYP2D6HSD11B1HCAR1 | |
| SCHEMBL25068975 | 0.83 | PRMT5 (0.44) | PRMT5EGFRCYP2D6HSD11B1KCNH2 | |
| SCHEMBL26606547 | 0.82 | EGFR (0.43) | PRMT5EGFRCYP2D6HSD11B1HCAR1 | |
| SCHEMBL26132563 | 0.82 | EGFR (0.43) | PRMT5EGFRCYP2D6HSD11B1HCAR1 | |
| SCHEMBL25068977 | 0.77 | PRMT5 (0.51) | PRMT5HSD11B1HCAR1GAAOPRM1 | |
| SCHEMBL24458045 | 0.77 | PRMT5 (0.51) | PRMT5HSD11B1HCAR1GAAOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022106902-A2 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2022-05-27 | — | — | WO | disclosed |