Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 16/20 | 0.40 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31523865 | 1.00 | BTK (0.40) | BTKERBB3FGFR4EGFRLCK | |
| SCHEMBL24458481 | 0.91 | BTK (0.42) | BTKERBB3FGFR4EGFRLCK | |
| SCHEMBL31523749 | 0.91 | BTK (0.42) | BTKERBB3FGFR4EGFRLCK | |
| SCHEMBL31523830 | 0.89 | BTK (0.43) | BTKERBB3EGFRLCKSRC | |
| SCHEMBL24458580 | 0.89 | BTK (0.43) | BTKERBB3EGFRLCKSRC | |
| SCHEMBL24458673 | 0.89 | BTK (0.42) | BTKEGFRLCKSRCKDR | |
| SCHEMBL31523950 | 0.89 | BTK (0.42) | BTKEGFRLCKSRCKDR | |
| SCHEMBL24459046 | 0.87 | BTK (0.50) | BTKEGFRLCKSRCKDR | |
| SCHEMBL24458533 | 0.83 | BTK (0.45) | BTKEGFRLCKSRCKDR | |
| SCHEMBL31523835 | 0.83 | BTK (0.45) | BTKEGFRLCKSRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |