Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.50 |
| ▸ | LCK | P06239 | 4/20 | 0.42 |
| ▸ | KDR | P35968 | 4/20 | 0.42 |
| ▸ | TEK | Q02763 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | BLK | P51451 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | TEC | P42680 | 1/20 | 0.41 |
| ▸ | TXK | P42681 | 1/20 | 0.41 |
| ▸ | BMX | P51813 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24458580 | 0.91 | BTK (0.43) | BTKLCKKDRTEKSRC | |
| SCHEMBL31523830 | 0.91 | BTK (0.43) | BTKLCKKDRTEKSRC | |
| SCHEMBL31523856 | 0.90 | BTK (0.49) | BTKLCKKDRTEKSRC | |
| SCHEMBL24458899 | 0.90 | BTK (0.55) | BTKLCKKDRTEKSRC | |
| SCHEMBL24459131 | 0.87 | BTK (0.53) | BTKLCKKDRSRCBLK | |
| SCHEMBL24459101 | 0.87 | BTK (0.53) | BTKLCKKDRSRCBLK | |
| SCHEMBL24458483 | 0.87 | BTK (0.53) | BTKLCKKDRSRCBLK | |
| SCHEMBL24458634 | 0.87 | BTK (0.40) | BTKLCKKDRTEKSRC | |
| SCHEMBL31523865 | 0.87 | BTK (0.40) | BTKLCKKDRTEKSRC | |
| SCHEMBL24458675 | 0.84 | BTK (0.54) | BTKLCKKDRSRCBLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109551-A1 | SRC INHIBITORS AND USES THEREOF | RELAY THERAPEUTICS, INC. (US) | 2022-05-27 | — | — | WO | disclosed |