SCHEMBL24459385

SCHEMBL24459385

C=C(C)CC(C)(C)CC(=C)N

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24782965 0.80 TDP1 (0.38) TDP1
SCHEMBL19590614 0.76
SCHEMBL24385960 0.76
SCHEMBL789350 0.72
SCHEMBL10532985 0.72
SCHEMBL16375439 0.72 KDM4E (0.50) TDP1
SCHEMBL18523103 0.72 CYP2D6 (0.30) TDP1
SCHEMBL2757915 0.71
SCHEMBL22167507 0.70 TDP1 (0.32) HSD17B10TDP1
SCHEMBL1024519 0.70 HSD17B10 (0.32) HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022106614-A1 PROCESSES FOR PREPARING ARIMOCLOMOL CITRATE AND INTERMEDIATES THEREOF ORPHAZYME A/S (DK) 2022-05-27 WO disclosed