⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20833084 | 0.77 | — | — | |
| SCHEMBL23287927 | 0.75 | — | — | |
| SCHEMBL25469271 | 0.75 | — | — | |
| SCHEMBL24385960 | 0.73 | — | — | |
| SCHEMBL19590614 | 0.73 | — | — | |
| SCHEMBL819553 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL21390692 | 0.72 | — | — | |
| SCHEMBL24459385 | 0.71 | HSD17B10 (0.30) | — | |
| SCHEMBL3232065 | 0.71 | TDP1 (0.41) | — | |
| SCHEMBL97535 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312648-A1 | PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES | YUYU PHARMA, INC. (KR) | 2023-10-05 | — | — | US | disclosed |
| US-20230159488-A1 | APPLICATION OF HETEROCYCLIC COMPOUND CONTAINING AT LEAST TWO SULFUR ATOMS IN PREPARING NANO-VACCINE AND PREPARED NANO-VACCINE | Suzhou WEAST Biotechnology Co., Ltd. (CN) | 2023-05-25 | — | — | US | disclosed |
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |
| US-20230146455-A1 | TREATMENT OF INFLAMMATORY DISEASES WITH PEPTIDES AND PHARMACEUTICAL COMPOSITIONS | YUYU PHARMA, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| WO-2023000962-A1 | CORE-SHELL QUANTUM DOT, QUANTUM DOT LIGHT-EMITTING DEVICE, DISPLAY APPARATUS AND MANUFACTURING METHOD | 京东方科技集团股份有限公司 | 2023-01-26 | — | — | WO | disclosed |
| US-10669252-B2 | Benzazepine derivative, preparation method, pharmaceutical composition and use thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2020-06-02 | — | — | US | disclosed |
| US-10544104-B2 | Compositions and methods for treating toxoplasmosis, cryptosporidiosis, and other apicomplexan protozoan related diseases | University of Washington Through its Center for Co (US) | 2020-01-28 | — | — | US | disclosed |
| CN-110256297-A | A kind of preparation method of N-Boc- (R) -2- amino -4,4- dimethyl valeric acid | 爱斯特（成都）生物制药股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-106458994-B | Biaryl kinase inhibitor | 百时美施贵宝公司 | 2019-09-13 | — | — | CN | disclosed |
| US-20190152941-A1 | BENZAZEPINE DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2019-05-23 | — | — | US | disclosed |
| WO-2017060854-A1 | BIARYL PYRAZOLES AS NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-04-13 | — | — | WO | disclosed |
| WO-2017040797-A1 | COATINGS WITH MOLECULAR FLEXIBILITY FOR ICE ADHESION MITIGATION | UNITED STATES OF AMERICAN as represented by THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 2017-03-09 | — | — | WO | disclosed |
| CN-106458994-A | Biaryl kinase inhibitors | 百时美施贵宝公司 | 2017-02-22 | — | — | CN | disclosed |
| US-20150045357-A1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-02-12 | — | — | US | disclosed |
| US-8362267-B2 | Benzophenone thiazole derivatives useful for inhibiting formation of microtubule and method for producing the same | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2013-01-29 | — | — | US | disclosed |
| US-8304423-B2 | Modulators of muscarinic receptors | VERTEX PHARMACEUTICAL INCORPORATED (US) | 2012-11-06 | — | — | US | disclosed |
| US-20120196857-A9 | Modulators of Muscarinic Receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-08-02 | — | — | US | disclosed |
| US-20120004226-A1 | Modulators of Muscarinic Receptors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-01-05 | — | — | US | disclosed |
| US-20110021582-A1 | BENZOPHENONE THIAZOLE DERIVATIVES USEFUL FOR INHIBITING FORMATION OF MICROTUBULE AND METHOD FOR PRODUCING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2011-01-27 | — | — | US | disclosed |
| US-20080051326-A1 | Antiinfective Lipopeptides | CUBIST PHARMACEUTICALS, INC. | 2008-02-28 | — | — | US | disclosed |