Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2461468 | 0.81 | DPP4 (0.42) | PTGS2HSD17B10KDM4EMAPK1CHRM2 | |
| SCHEMBL13221599 | 0.81 | PDCD1 (0.46) | PTGS2HSD17B10KDM4EMAPK1CHRM2 | |
| SCHEMBL31454790 | 0.79 | KDM4E (0.40) | PTGS2HSD17B10KDM4EMAPK1CHRM2 | |
| SCHEMBL13744406 | 0.77 | KDM4E (0.39) | PTGS2HSD17B10KDM4EMAPK1CHRM2 | |
| SCHEMBL2460103 | 0.74 | PTGS2 (0.45) | PTGS2HSD17B10KDM4EMAPK1CHRM2 | |
| SCHEMBL13158248 | 0.72 | CHRM2 (0.54) | PTGS2HSD17B10KDM4EMAPK1CHRM2 | |
| SCHEMBL2461470 | 0.68 | HSD17B10 (0.42) | PTGS2HSD17B10KDM4EMAPK1CHRM2 | |
| SCHEMBL3973961 | 0.67 | KDM4E (0.62) | PTGS2HSD17B10KDM4EMAPK1NPC1 | |
| SCHEMBL10903070 | 0.66 | PTGS2 (0.52) | PTGS2HSD17B10KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL17281581 | 0.65 | SMN1; SMN2 (0.41) | KDM4ERAB9ASMN1; SMN2HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109078-A1 | AROMATIC BORON-CONTAINING COMPOUNDS AND INSULIN ANALOGS | PROTOMER TECHNOLOGIES INC. (US) | 2022-05-27 | — | — | WO | disclosed |