Bromide

Bromide

SCHEMBL2445980

[Br-].c1ccc([P+](c2ccccc2)(c2ccccc2)C2CCCCC2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.38
GAA P10253 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SLC18A3 Q16572 1/20 0.34
HPGD P15428 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
HIF1A Q16665 1/20 0.33
EPHX2 P34913 2/20 0.32
KDM4E B2RXH2 2/20 0.32
EPHX1 P07099 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PTPRC P08575 1/20 0.32
PTPRF P10586 1/20 0.32
PTPN1 P18031 1/20 0.32
CDC25B P30305 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL7633092 1.00 IDO1 (0.38) IDO1GAAL3MBTL1SLC18A3HPGD
Bromide SCHEMBL3322091 1.00 IDO1 (0.38) IDO1GAAL3MBTL1SLC18A3HPGD
Bromide SCHEMBL10533526 0.98 IDO1 (0.37) IDO1GAAL3MBTL1SLC18A3HPGD
Bromide SCHEMBL2447458 0.98 GAA (0.36) IDO1GAAL3MBTL1SLC18A3HPGD
SCHEMBL29515524 0.98 IDO1 (0.39) IDO1GAAL3MBTL1SLC18A3HPGD
Hydrochloric Acid SCHEMBL7629171 0.95 IDO1 (0.38) IDO1GAAL3MBTL1SLC18A3HPGD
Iodide SCHEMBL7629435 0.95 IDO1 (0.38) IDO1GAAL3MBTL1SLC18A3HPGD
Iodide SCHEMBL7628894 0.95 IDO1 (0.38) IDO1GAAL3MBTL1SLC18A3HPGD
Hydrochloric Acid SCHEMBL4387947 0.95 IDO1 (0.38) IDO1GAAL3MBTL1SLC18A3HPGD
Iodide SCHEMBL7633294 0.95 IDO1 (0.38) IDO1GAAL3MBTL1SLC18A3HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316575-B1 MELT TRANSESTERIFICATION OF DIOL COMPOUND AND CARBOANTE COMPOUND USING CATALYST COMPRISING A PHOSPHORUS-CONTAINING BASIC COMPOUND QUATERNARY PHOSPHONIUM SALT TO FORM POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2001-11-13 US claimed
EP-0329021-B1 Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds DOW CHEMICAL CO (US) 1994-01-26 EP claimed
EP-0329021-A2 Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds THE DOW CHEMICAL COMPANY (US) 1989-08-23 EP claimed
US-4808692-A Preparation of advanced epoxy resins from epoxy resins and dihydric phenols in the presence of phosphonium compounds THE DOW CHEMICAL COMPANY (US) 1989-02-28 US claimed
US-20250340574-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2025-11-06 US disclosed
EP-3700956-B1 CATALYSTS FOR MAKING OXAZOLIDINONE MATERIALS HUNTSMAN INT LLC (US) 2025-04-09 EP disclosed
EP-4504739-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2025-02-12 EP disclosed
CN-119308018-A Chiral zinc-based metal halide monocrystal material and preparation method and application thereof 江西铜业技术研究院有限公司 2025-01-14 CN disclosed
CN-118373846-A Cerium (III) -based metal halide transparent glass scintillator and preparation method and application thereof 中国计量大学 2024-07-23 CN disclosed
US-20230374038-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS (SAN DIEGO) LLC 2023-11-23 US disclosed
WO-2023196429-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2023-10-12 WO disclosed
EP-4225761-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Vertex Pharmaceuticals Incorporated (US) 2023-08-16 EP disclosed
US-5122523-A Hypotensive agents BANYU PHARMACEUTICAL CO., LTD. (JP) 1992-06-16 US disclosed
WO-1991016888-A1 SPIRO[BENZOFURANCYCLOALKANE]CARBOXAMIDES AS 5HT3 ANTAGONISTS RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) 1991-11-14 WO disclosed
EP-0414160-A2 Process for preparing advanced epoxy resins THE DOW CHEMICAL COMPANY (US) 1991-02-27 EP disclosed
WO-1991001975-A1 CYCLOALKYLENAZOLES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE TO MANUFACTURE DRUGS SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) 1991-02-21 WO disclosed
EP-0411735-A1 Cycloalkylenazoles, process for their preparation, pharmaceutical preparations containing them and their use for the preparation of medicines SCHERING AKTIENGESELLSCHAFT (DE) 1991-02-06 EP disclosed
EP-0329021-A2 Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds THE DOW CHEMICAL COMPANY (US) 1989-08-23 EP disclosed
EP-0309766-A2 N-acylamino acid derivatives and their use BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-04-05 EP disclosed
US-4808692-A Preparation of advanced epoxy resins from epoxy resins and dihydric phenols in the presence of phosphonium compounds THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230374038-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B IDO1 4752/4885GAA 1085/4885L3MBTL1 4286/4885
US-20250340574-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B IDO1 4795/4885GAA 956/4885L3MBTL1 4197/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.