Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7629435 | 1.00 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Iodide SCHEMBL7628894 | 1.00 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Iodide SCHEMBL6591776 | 0.98 | GAA (0.36) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| SCHEMBL29515524 | 0.98 | IDO1 (0.39) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Hydrochloric Acid SCHEMBL4387947 | 0.95 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Hydrochloric Acid SCHEMBL7635385 | 0.95 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Bromide SCHEMBL7633092 | 0.95 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Bromide SCHEMBL2445980 | 0.95 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Hydrochloric Acid SCHEMBL7629171 | 0.95 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD | |
| Bromide SCHEMBL3322091 | 0.95 | IDO1 (0.38) | IDO1GAAL3MBTL1SLC18A3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780452-B1 | Aqueous paint | TOYO SEIKAN KAISHA LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| US-5763507-A | EPOXY ACRYLATE RESIN | TOYO SEIKAN KAISHA, LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0414160-B1 | Process for preparing advanced epoxy resins | DOW CHEMICAL CO (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5310854-A | Solvent, coatings for beverage cans | THE DOW CHEMICAL COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0329021-B1 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | disclosed |
| EP-0414160-A2 | Process for preparing advanced epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0329021-A2 | Preparation of advanced epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-08-23 | — | — | EP | disclosed |
| US-4808692-A | Preparation of advanced epoxy resins from epoxy resins and dihydric phenols in the presence of phosphonium compounds | THE DOW CHEMICAL COMPANY (US) | 1989-02-28 | — | — | US | disclosed |