Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 13/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.51 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MYLK | Q15746 | 1/20 | 0.46 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771732 | 0.87 | P2RX1 (0.64) | P2RX1P2RX4P2RX7TAS1R3TAS1R1 | |
| SCHEMBL18341307 | 0.87 | P2RX1 (0.64) | P2RX1P2RX4P2RX7TAS1R3TAS1R1 | |
| SCHEMBL24460206 | 0.78 | TAS1R3 (0.72) | P2RX1P2RX4P2RX7TAS1R3TAS1R1 | |
| SCHEMBL18341338 | 0.76 | P2RX1 (0.68) | P2RX1P2RX4P2RX7TMPRSS4KCNMA1 | |
| SCHEMBL30771722 | 0.76 | P2RX1 (0.68) | P2RX1P2RX4P2RX7TMPRSS4KCNMA1 | |
| SCHEMBL330391 | 0.76 | P2RX1 (0.66) | P2RX1P2RX4P2RX7TAS1R3TAS1R1 | |
| SCHEMBL4264405 | 0.73 | P2RX1 (0.72) | P2RX1P2RX4P2RX7TMPRSS4KCNMA1 | |
| SCHEMBL24460167 | 0.73 | P2RX1 (0.71) | P2RX1P2RX4P2RX7TAS1R3TAS1R1 | |
| SCHEMBL31238369 | 0.72 | TAS1R3 (0.86) | P2RX1P2RX4P2RX7TAS1R3TAS1R1 | |
| SCHEMBL13189556 | 0.71 | P2RX1 (0.68) | P2RX1P2RX4P2RX7TMPRSS4KCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022109148-A1 | SMALL MOLECULE INHIBITORS OF SARS-COV-2 INFECTIONS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-05-27 | — | — | WO | disclosed |