Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 5/20 | 0.57 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.56 |
| ▸ | CDK2 | P24941 | 6/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CDK7 | P50613 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CCNH | P51946 | 1/20 | 0.47 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771747 | 1.00 | KCNMA1 (0.57) | KCNMA1CCNE1CDK2CDK5P2RX1 | |
| SCHEMBL5835944 | 0.89 | CDK2 (0.57) | KCNMA1CCNE1CDK2CDK5CCNT1 | |
| SCHEMBL13055666 | 0.88 | KCNMA1 (0.57) | KCNMA1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL5835649 | 0.86 | CCNE1 (0.57) | CCNE1CDK2CDK5CCNT1ALDH1A1 | |
| SCHEMBL5835868 | 0.85 | KCNMA1 (0.61) | KCNMA1CCNE1CDK2CDK5ALDH1A1 | |
| SCHEMBL5835711 | 0.84 | CDK2 (0.55) | CCNE1CDK2CDK5CCNT1ALDH1A1 | |
| SCHEMBL10114085 | 0.84 | KCNMA1 (0.61) | KCNMA1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL24460247 | 0.83 | CDK2 (0.54) | KCNMA1CCNE1CDK2CDK5STAT3 | |
| SCHEMBL30472740 | 0.83 | KCNMA1 (0.64) | KCNMA1P2RX1TMPRSS4P2RX4P2RX7 | |
| SCHEMBL5836737 | 0.83 | KMT2A (0.61) | CCNE1CDK2CDK5STAT3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION | 2024-01-04 | — | — | US | claimed |
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION | 2024-01-04 | — | — | US | disclosed |
| WO-2022109148-A1 | SMALL MOLECULE INHIBITORS OF SARS-COV-2 INFECTIONS | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002332-A1 | Small Molecule Inhibitors of SARS-CoV-2 Infections | ACE2, ACE, TMPRSS2 | KCNMA1 3777/4885CCNE1 2462/4885CDK2 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.