Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21014711 | 0.95 | TP53 (0.34) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL24312359 | 0.87 | POLL (0.33) | LMNAMAPTCYP2C9ALOX15CYP2C19 | |
| SCHEMBL26617703 | 0.74 | CA1 (0.38) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL26617698 | 0.74 | CA1 (0.38) | TP53POLBSMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL27244359 | 0.69 | MAP1LC3B (0.33) | LMNAMAPTCYP2C9ALOX15CYP2C19 | |
| SCHEMBL21134123 | 0.69 | MAP1LC3B (0.33) | LMNAMAPTCYP2C9ALOX15CYP2C19 | |
| SCHEMBL27244319 | 0.69 | MAP1LC3B (0.33) | LMNAMAPTCYP2C9ALOX15CYP2C19 | |
| SCHEMBL27244325 | 0.69 | MAP1LC3B (0.33) | LMNAMAPTCYP2C9ALOX15CYP2C19 | |
| SCHEMBL1617387 | 0.69 | MAPT (0.35) | TDP1L3MBTL1LMNAMAPTCYP2C9 | |
| SCHEMBL1617390 | 0.69 | MAPT (0.35) | TDP1L3MBTL1LMNAMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006036-A1 | TETRACYCLIC COMPOUND USED AS CDC7 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-06-01 | — | — | EP | disclosed |