SCHEMBL24465294

SCHEMBL24465294

CN(C(=O)COCC1CO1)S(=O)(=O)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
MAPK1 P28482 1/20 0.37
ALDH1A1 P00352 4/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.31
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24465390 0.84 GPBAR1 (0.31)
SCHEMBL24453010 0.83 TSHR (0.33) TSHRMAPK1ALDH1A1TP53CYP3A4
SCHEMBL24453011 0.77 TSHR (0.37) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL24465341 0.75 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4
SCHEMBL24465387 0.73
SCHEMBL24465430 0.71 TSHR (0.40) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL24452795 0.71 TSHR (0.44) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
Trifluoromethanesulfonic Acid SCHEMBL28763355 0.71 TSHR (0.44) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL24452796 0.70 TSHR (0.46) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL24453018 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4006921-A2 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE Shin-Etsu Chemical Co., Ltd. (JP) 2022-06-01 EP disclosed