Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24466708 | 0.83 | AURKA (0.34) | AURKAAURKB | |
| SCHEMBL23863815 | 0.81 | AURKA (0.34) | AURKAAURKB | |
| SCHEMBL20919458 | 0.80 | AURKA (0.33) | AURKAAURKB | |
| SCHEMBL20919513 | 0.79 | AURKA (0.33) | AURKAAURKB | |
| SCHEMBL30704800 | 0.78 | AURKA (0.32) | AURKAAURKB | |
| SCHEMBL20919318 | 0.76 | AURKA (0.34) | AURKAAURKB | |
| SCHEMBL19748809 | 0.76 | PTGS2 (0.42) | AURKAAURKB | |
| SCHEMBL30986326 | 0.76 | AURKA (0.32) | AURKAAURKB | |
| Trifluoroacetic Acid SCHEMBL20984157 | 0.75 | IKBKB (0.31) | AURKAAURKB | |
| SCHEMBL19746883 | 0.75 | PIK3CG (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4006034-A1 | CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED BY TERTIARY HYDROXY GROUPS AS PI3K-GAMMA INHIBITORS | Incyte Corporation (US) | 2022-06-01 | — | — | EP | disclosed |