Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.56 |
| ▸ | FADS1 | O60427 | 1/20 | 0.56 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.51 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29808519 | 1.00 | EGFR (0.56) | EGFRFADS1PIP4K2CFLT1IRAK4 | |
| SCHEMBL5329628 | 0.81 | MEN1 (0.65) | EGFRFADS1PIP4K2CFLT1MEN1 | |
| SCHEMBL5314379 | 0.80 | EGFR (0.56) | EGFRFADS1PIP4K2CFLT1AURKA | |
| SCHEMBL5315196 | 0.80 | EGFR (0.67) | EGFRFADS1PIP4K2CFLT1AURKA | |
| Hydrochloric Acid SCHEMBL5468355 | 0.80 | EGFR (0.64) | EGFRFADS1PIP4K2CFLT1MEN1 | |
| SCHEMBL5455935 | 0.79 | EGFR (0.62) | EGFRFADS1PIP4K2CFLT1IRAK4 | |
| Hydrochloric Acid SCHEMBL5472957 | 0.79 | EGFR (0.56) | EGFRFADS1PIP4K2CFLT1AURKA | |
| SCHEMBL5468539 | 0.79 | PIP4K2C (0.64) | EGFRFADS1PIP4K2CFLT1AURKA | |
| Hydrochloric Acid SCHEMBL5472994 | 0.79 | EGFR (0.65) | EGFRFADS1PIP4K2CFLT1AURKA | |
| SCHEMBL5313058 | 0.78 | EGFR (0.66) | EGFRFADS1PIP4K2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220402935-A1 | HETEROCYCLIC COMPOUND | FIMECS, INC. (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-4006037-A1 | HETEROCYCLIC COMPOUND | Fimecs, Inc. (JP) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402935-A1 | HETEROCYCLIC COMPOUND | IRAK1, IRAK2, IRAK4 | EGFR 814/4885FADS1 4432/4885PIP4K2C 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.