Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.81 |
| ▸ | BTK | Q06187 | 19/20 | 0.81 |
| ▸ | TXK | P42681 | 17/20 | 0.81 |
| ▸ | ITK | Q08881 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20161875 | 0.90 | JAK3 (1.00) | JAK3BTKTXKITK | |
| SCHEMBL20161557 | 0.83 | JAK3 (1.00) | JAK3BTKTXKITK | |
| SCHEMBL24467289 | 0.80 | BTK (0.84) | JAK3BTKTXKITK | |
| SCHEMBL24467295 | 0.80 | JAK3 (0.81) | JAK3BTKTXKITK | |
| SCHEMBL23366050 | 0.78 | BTK (0.73) | JAK3BTKTXKITK | |
| SCHEMBL20161874 | 0.77 | JAK3 (1.00) | JAK3BTKTXKITK | |
| SCHEMBL20161551 | 0.76 | BTK (0.83) | JAK3BTKTXKITK | |
| SCHEMBL24467340 | 0.76 | JAK3 (0.82) | JAK3BTKTXKITK | |
| SCHEMBL20161676 | 0.75 | TXK (1.00) | JAK3BTKTXKITK | |
| SCHEMBL24467217 | 0.75 | TXK (1.00) | JAK3BTKTXKITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3534899-B1 | COMPOUNDS AND METHODS FOR MODULATING INTERLEUKIN-2-INDUCIBLE T-CELL KINASE | CORVUS PHARMACEUTICALS INC (US) | 2022-06-01 | — | — | EP | disclosed |