Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446779 | 0.87 | MET (0.73) | METKCNH2 | |
| SCHEMBL2450527 | 0.86 | MET (0.72) | METKCNH2 | |
| SCHEMBL2447481 | 0.85 | MET (0.72) | METKCNH2 | |
| SCHEMBL2447158 | 0.84 | MET (0.82) | METKCNH2 | |
| SCHEMBL2326202 | 0.82 | MET (0.68) | METKCNH2 | |
| SCHEMBL2446697 | 0.82 | MET (0.71) | METKCNH2 | |
| SCHEMBL2450933 | 0.82 | MET (0.82) | METKCNH2 | |
| SCHEMBL2445229 | 0.82 | MET (0.73) | METKCNH2 | |
| SCHEMBL2450079 | 0.82 | MET (0.70) | METKCNH2 | |
| SCHEMBL2446747 | 0.81 | MET (0.67) | METKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896421-B1 | BENZOCYCLOHEPTAPYRIDINES AS INHIBITORS OF THE RECEPTOR TYROSINE KINASE MET | MERCK SHARP & DOHME (US) | 2011-09-14 | — | — | EP | claimed |