SCHEMBL24467490

SCHEMBL24467490

CNc1nc2cc(C)cc(OCCCOC)c2n1C/C=C/Cn1c(NC)nc2cc(C(N)=O)cc(OCCCOC)c21

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 20/20 0.57
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25078712 0.82 STING1 (0.85) STING1CYP3A4
SCHEMBL24611738 0.80 STING1 (0.49) STING1CYP3A4
SCHEMBL19451816 0.80 STING1 (0.75) STING1CYP3A4
SCHEMBL19451735 0.80 STING1 (0.85) STING1CYP3A4
SCHEMBL19449010 0.79 STING1 (0.55) STING1
SCHEMBL24467473 0.78 STING1 (0.90) STING1CYP3A4
SCHEMBL23077572 0.78 STING1 (0.84) STING1CYP3A4
SCHEMBL23077574 0.78 STING1 (0.84) STING1CYP3A4
SCHEMBL24611699 0.78 STING1 (0.79) STING1CYP3A4
SCHEMBL19451799 0.78 STING1 (0.79) STING1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3440076-B1 HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS GLAXOSMITHKLINE IP DEV LTD (GB) 2022-06-01 EP disclosed