Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.71 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451841 | 0.92 | STING1 (0.84) | STING1TBK1 | |
| SCHEMBL23709427 | 0.92 | STING1 (0.69) | STING1TBK1 | |
| SCHEMBL23709457 | 0.90 | STING1 (0.67) | STING1TBK1 | |
| SCHEMBL20075782 | 0.89 | STING1 (0.75) | STING1TBK1 | |
| SCHEMBL24467617 | 0.88 | STING1 (0.73) | STING1TBK1 | |
| SCHEMBL22428327 | 0.87 | STING1 (0.73) | STING1TBK1 | |
| SCHEMBL23709331 | 0.86 | STING1 (0.62) | STING1TBK1 | |
| SCHEMBL19451887 | 0.85 | STING1 (0.85) | STING1TBK1 | |
| SCHEMBL19451771 | 0.85 | STING1 (0.79) | STING1TBK1 | |
| SCHEMBL19451608 | 0.85 | STING1 (0.84) | STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440076-B1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2022-06-01 | — | — | EP | disclosed |