Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 20/20 | 0.62 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22151634 | 0.93 | STING1 (0.61) | STING1TBK1 | |
| SCHEMBL19451755 | 0.92 | STING1 (0.70) | STING1TBK1 | |
| SCHEMBL28919520 | 0.92 | STING1 (0.70) | STING1TBK1 | |
| SCHEMBL23709447 | 0.92 | STING1 (0.65) | STING1TBK1 | |
| SCHEMBL21156976 | 0.88 | STING1 (0.61) | STING1TBK1 | |
| SCHEMBL23709337 | 0.88 | STING1 (0.61) | STING1TBK1 | |
| SCHEMBL23346489 | 0.86 | STING1 (0.59) | STING1TBK1 | |
| SCHEMBL24467597 | 0.86 | STING1 (0.71) | STING1TBK1 | |
| SCHEMBL23252150 | 0.86 | STING1 (0.58) | STING1TBK1 | |
| SCHEMBL23252124 | 0.86 | STING1 (0.58) | STING1TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238172-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS AND METHODS OF USING THE SAME | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238172-A1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS AND METHODS OF USING THE SAME | AADAC, TAF15, HDAC10 | STING1 748/4885TBK1 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.