Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 19/20 | 0.76 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.73 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451797 | 0.97 | STING1 (0.78) | STING1TBK1ENPP1 | |
| SCHEMBL28597027 | 0.89 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL19451477 | 0.89 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL29702099 | 0.89 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL19437661 | 0.87 | STING1 (0.87) | STING1TBK1ENPP1 | |
| SCHEMBL19437599 | 0.87 | STING1 (1.00) | STING1TBK1 | |
| SCHEMBL29702073 | 0.86 | STING1 (0.93) | STING1TBK1ENPP1 | |
| SCHEMBL19451762 | 0.86 | STING1 (0.93) | STING1TBK1ENPP1 | |
| SCHEMBL19451865 | 0.86 | STING1 (0.76) | STING1TBK1ENPP1 | |
| SCHEMBL24467557 | 0.86 | STING1 (0.76) | STING1TBK1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440076-B1 | HETEROCYCLIC AMIDES USEFUL AS PROTEIN MODULATORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2022-06-01 | — | — | EP | disclosed |