Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20643367 | 0.98 | TSHR (0.44) | TSHRMAPTHSD17B10CYP3A4KDM4E | |
| SCHEMBL22856301 | 0.96 | TSHR (0.43) | TSHRMAPTHSD17B10CYP3A4KDM4E | |
| SCHEMBL22849681 | 0.96 | TSHR (0.43) | TSHRMAPTHSD17B10CYP3A4KDM4E | |
| SCHEMBL23334509 | 0.96 | TSHR (0.43) | TSHRMAPTHSD17B10CYP3A4KDM4E | |
| SCHEMBL22906479 | 0.91 | TSHR (0.43) | TSHRMAPTHSD17B10CYP3A4ADRB2 | |
| SCHEMBL20562604 | 0.91 | KDM4E (0.39) | KDM4ECYP1A2CYP2D6CYP2C19ADRB2 | |
| SCHEMBL25123786 | 0.89 | HTT (0.47) | TSHRMAPTCYP3A4KDM4ECYP1A2 | |
| SCHEMBL14442979 | 0.89 | TSHR (0.44) | TSHRMAPTHSD17B10CYP3A4ADRB2 | |
| SCHEMBL20562681 | 0.89 | KDM4E (0.41) | KDM4ECYP1A2CYP2D6CYP2C19ADRB2 | |
| SCHEMBL20562213 | 0.89 | KDM4E (0.41) | KDM4ECYP1A2CYP2D6CYP2C19ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220168430-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | ARBUTUS BIOPHARMA CORPORATION (US) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220168430-A1 | THERAPEUTIC METHODS FOR TREATING HEPATITIS B | HAVCR2, HDGF, FABP1 | TSHR 3050/4885MAPT 4046/4885HSD17B10 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.