⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14890555 | 0.97 | MAPT (0.50) | — | |
| SCHEMBL11319968 | 0.76 | ALDH1A1 (0.45) | — | |
| SCHEMBL53472 | 0.75 | — | — | |
| SCHEMBL10535057 | 0.74 | ALDH1A1 (0.44) | — | |
| SCHEMBL2447843 | 0.73 | — | — | |
| SCHEMBL73049 | 0.73 | — | — | |
| SCHEMBL11571232 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL4115598 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL29010312 | 0.72 | — | — | |
| Silver SCHEMBL30466753 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103613510-B | Simple method for dehalogenating alpha-halogenated compounds | UNIV ZHEJIANG TECHNOLOGY | 2015-05-06 | — | — | CN | claimed |
| CN-103613510-A | Simple method for dehalogenating alpha-halogenated compounds | UNIV ZHEJIANG TECHNOLOGY | 2014-03-05 | — | — | CN | claimed |
| US-4992585-A | Reacting N-methylacetoacetamide with chlorie to produce A-chloro-N-methyl acetoacetamide | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | claimed |
| EP-0166685-B1 | PROCESS FOR THE PREPARATION OF ALPHA-CHLOROACETOACETIC-ACID MONOMETHYL AMIDE | CIBA-GEIGY AG (CH) | 1988-12-28 | — | — | EP | claimed |
| CN-87102556-A | Chlorination technology of permanently effective phosphorous improves and wastewater treatment | — | 1988-10-12 | — | — | CN | claimed |
| US-4235818-A | Process for producing alpha-monochloroacetoacetic acid monomethylamide | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | claimed |
| US-9943498-B2 | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias | VIFOR (INTERNATIONAL) AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-9943498-B2 | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias | VIFOR (INTERNATIONAL) AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-9943498-B2 | Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias | VIFOR (INTERNATIONAL) AG (CH) | 2018-04-17 | — | — | US | disclosed |
| EP-2549991-B1 | FE(III) COMPLEX COMPOUNDS FOR TREATING AND PROPHYLAXIS FOR ANAEMIA SYMPTOMS AND ANAEMIA | VIFOR (INTERNATIONAL) AG (CH) | 2017-11-22 | — | — | EP | disclosed |
| EP-2549991-B1 | FE(III) COMPLEX COMPOUNDS FOR TREATING AND PROPHYLAXIS FOR ANAEMIA SYMPTOMS AND ANAEMIA | VIFOR (INTERNATIONAL) AG (CH) | 2017-11-22 | — | — | EP | disclosed |
| US-20160310459-A1 | Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias | VIFOR (INTERNATIONAL) AG (CH) | 2016-10-27 | — | — | US | disclosed |
| US-20160310459-A1 | Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias | VIFOR (INTERNATIONAL) AG (CH) | 2016-10-27 | — | — | US | disclosed |
| EP-0005849-B1 | PROCESS FOR PREPARING ALPHA-CHLORO-N-MONOALKYL-ACETOACETAMIDES | Wacker-Chemie GmbH (DE) | 1981-10-21 | — | — | EP | disclosed |
| US-4235818-A | Process for producing alpha-monochloroacetoacetic acid monomethylamide | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4235818-A | Process for producing alpha-monochloroacetoacetic acid monomethylamide | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4235818-A | Process for producing alpha-monochloroacetoacetic acid monomethylamide | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4207259-A | WATER AS SOLVENT | WACKER-CHEMIE GMBH (DE) | 1980-06-10 | — | — | US | disclosed |
| EP-0011169-A1 | Process for the stereo-selective preparation of (E),(E)-diolefines | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |
| EP-0005849-A1 | Process for preparing alpha-chloro-N-monoalkyl-acetoacetamides | Wacker-Chemie GmbH (DE) | 1979-12-12 | — | — | EP | disclosed |