Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2447009 | 1.00 | NR3C1 (0.50) | NR3C1PGRALDH1A1MAPT | |
| SCHEMBL2450577 | 0.87 | NR3C1 (0.47) | NR3C1 | |
| SCHEMBL2450579 | 0.87 | NR3C1 (0.47) | NR3C1 | |
| SCHEMBL1142450 | 0.81 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL1142453 | 0.81 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL1141814 | 0.79 | NR3C1 (0.49) | NR3C1PGR | |
| SCHEMBL1141818 | 0.79 | NR3C1 (0.49) | NR3C1PGR | |
| SCHEMBL2442345 | 0.78 | NR3C1 (0.47) | NR3C1PGR | |
| SCHEMBL1142522 | 0.78 | NR3C1 (0.48) | NR3C1PGR | |
| SCHEMBL1142524 | 0.78 | NR3C1 (0.48) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896424-B1 | MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2011-09-21 | — | — | EP | disclosed |