Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.68 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.68 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.68 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SLC26A4 | O43511 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NMT2 | O60551 | 1/20 | 0.54 |
| ▸ | NMT1 | P30419 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24470576 | 0.91 | CASP3 (0.69) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL24470590 | 0.90 | CASP3 (0.68) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL24470543 | 0.88 | CASP3 (0.66) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL29713056 | 0.87 | CASP3 (0.64) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL24470923 | 0.87 | CASP3 (0.64) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL24470555 | 0.87 | CASP3 (0.64) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL24470909 | 0.85 | CASP3 (0.61) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL24470914 | 0.84 | CASP3 (0.60) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL24470625 | 0.83 | CASP3 (0.61) | CASP3SENP8SENP7SENP6HPGD | |
| SCHEMBL29104633 | 0.82 | CASP3 (0.58) | CASP3SENP8SENP7SENP6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116761796-A | Aryl derivatives for the treatment of TRPM3 mediated disorders | 勒芬天主教大学 | 2023-09-15 | — | — | CN | disclosed |
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |