Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | SLC26A4 | O43511 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30569436 | 1.00 | CASP3 (0.59) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL30569388 | 0.92 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713009 | 0.92 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470640 | 0.92 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470645 | 0.92 | CASP3 (0.54) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470658 | 0.91 | CASP3 (0.57) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713048 | 0.91 | CASP3 (0.57) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470819 | 0.90 | CASP3 (0.67) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470583 | 0.86 | CASP3 (0.69) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29712979 | 0.86 | CASP3 (0.55) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |