Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.53 |
| ▸ | SLC26A4 | O43511 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713065 | 1.00 | CASP3 (0.61) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470852 | 0.93 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713037 | 0.93 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713004 | 0.89 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470818 | 0.89 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29712966 | 0.89 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470853 | 0.89 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470839 | 0.89 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL29713059 | 0.89 | CASP3 (0.66) | CASP3SENP8SENP7SENP6L3MBTL1 | |
| SCHEMBL24470583 | 0.88 | CASP3 (0.69) | CASP3SENP8SENP7SENP6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |