Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29630289 | 1.00 | PTGS2 (0.62) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604878 | 0.88 | PTGS2 (0.60) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604909 | 0.86 | PTGS2 (0.67) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL18516741 | 0.83 | PTGS2 (0.76) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604929 | 0.83 | PTGS2 (0.55) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604999 | 0.83 | PTGS2 (0.58) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604961 | 0.83 | PTGS2 (0.55) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604935 | 0.83 | PTGS2 (0.60) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL31604856 | 0.82 | PTGS2 (0.54) | PTGS2ALDH1A1LMNAMAPK1MAPT | |
| SCHEMBL24470667 | 0.82 | MEN1 (0.71) | PTGS2ALDH1A1LMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |