Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 19/20 | 0.68 |
| ▸ | JAK2 | O60674 | 14/20 | 0.68 |
| ▸ | JAK3 | P52333 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24474769 | 0.91 | JAK1 (0.66) | JAK1JAK2 | |
| SCHEMBL24474853 | 0.90 | JAK1 (0.65) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL26078109 | 0.90 | JAK1 (0.67) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL25369910 | 0.87 | JAK1 (0.64) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL25407580 | 0.87 | JAK1 (0.74) | JAK1JAK2 | |
| SCHEMBL25370006 | 0.85 | JAK1 (0.79) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL25370003 | 0.85 | JAK1 (0.79) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL25407572 | 0.84 | JAK1 (0.69) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL25407562 | 0.83 | JAK1 (0.64) | JAK1JAK2JAK3KCNH2 | |
| SCHEMBL26067140 | 0.82 | JAK1 (0.77) | JAK1JAK2JAK3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111499-A1 | AMIDE COMPOUND, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 深圳铂立健医药有限公司 | 2022-06-02 | — | — | WO | disclosed |