Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336170 | 0.87 | CHRNB2 (0.45) | CHRNB2CHRNA7CHRNA4CHRNA5CYP1A2 | |
| SCHEMBL336171 | 0.87 | CHRNB2 (0.45) | CHRNB2CHRNA7CHRNA4CHRNA5CYP1A2 | |
| SCHEMBL8198672 | 0.85 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4CHRNA5OPRD1 | |
| SCHEMBL14077882 | 0.85 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4CHRNA5OPRD1 | |
| SCHEMBL13740779 | 0.85 | CHRNB2 (0.47) | CHRNB2CHRNA7CHRNA4CHRNA5OPRD1 | |
| Hydrochloric Acid SCHEMBL336873 | 0.83 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA4CHRNA5OPRD1 | |
| Hydrochloric Acid SCHEMBL21801329 | 0.83 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA4CHRNA5OPRD1 | |
| Hydrochloric Acid SCHEMBL4062254 | 0.83 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA4CHRNA5OPRD1 | |
| SCHEMBL14381443 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA7CHRNA4CHRNA5CYP1A2 | |
| SCHEMBL16120991 | 0.81 | CHRNB2 (0.42) | CHRNB2CHRNA7CHRNA4CHRNA5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113784758-B | Non-plant host cells producing tropane alkaloids (TA) and methods of making and using the same | 小利兰·斯坦福大学托管委员会 | 2025-03-07 | — | — | CN | claimed |
| CN-117500928-A | Tropane alkaloid transporter and method for producing tropane alkaloid using same | 小利兰·斯坦福大学托管委员会 | 2024-02-02 | — | — | CN | claimed |
| CN-114317631-B | Application of monoamine oxidase in preparation of topiroxone | 武汉大学 | 2023-11-07 | — | — | CN | claimed |
| CN-114292825-B | Synthesis method of tropinone | 武汉大学 | 2023-08-18 | — | — | CN | claimed |
| CN-114317631-A | Application of monoamine oxidase in preparation of tropinone | 武汉大学 | 2022-04-12 | — | — | CN | claimed |
| CN-114292825-A | Synthetic method of tropinone | 武汉大学 | 2022-04-08 | — | — | CN | claimed |
| CN-113784758-A | Non-plant host cells that produce Tropane Alkaloids (TA) and methods of making and using the same | 小利兰·斯坦福大学托管委员会 | 2021-12-10 | — | — | CN | claimed |
| CN-111826355-B | Scopolia acutangula P450 enzyme and application thereof in preparation of tropinone | 中国科学院分子植物科学卓越创新中心 | 2021-11-26 | — | — | CN | claimed |
| CN-111826357-B | Scopolia acutangula atypical III type polyketide synthase and application thereof | 中国科学院分子植物科学卓越创新中心 | 2021-11-19 | — | — | CN | claimed |
| CN-111826357-A | Scopolia acutangula atypical III type polyketide synthase and application thereof | 中国科学院分子植物科学卓越创新中心 | 2020-10-27 | — | — | CN | claimed |
| CN-111826355-A | Scopolia acutangula P450 enzyme and application thereof in preparation of tropinone | 中国科学院分子植物科学卓越创新中心 | 2020-10-27 | — | — | CN | claimed |
| CN-113784758-B | Non-plant host cells producing tropane alkaloids (TA) and methods of making and using the same | 小利兰·斯坦福大学托管委员会 | 2025-03-07 | — | — | CN | disclosed |
| CN-117500928-A | Tropane alkaloid transporter and method for producing tropane alkaloid using same | 小利兰·斯坦福大学托管委员会 | 2024-02-02 | — | — | CN | disclosed |
| CN-114317631-B | Application of monoamine oxidase in preparation of topiroxone | 武汉大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-114317631-B | Application of monoamine oxidase in preparation of topiroxone | 武汉大学 | 2023-11-07 | — | — | CN | disclosed |
| CN-113307884-A | Tropinone biosynthesis fusion protein and application and method thereof | 西南大学 | 2021-08-27 | — | — | CN | disclosed |
| CN-111826357-A | Scopolia acutangula atypical III type polyketide synthase and application thereof | 中国科学院分子植物科学卓越创新中心 | 2020-10-27 | — | — | CN | disclosed |
| CN-111826357-A | Scopolia acutangula atypical III type polyketide synthase and application thereof | 中国科学院分子植物科学卓越创新中心 | 2020-10-27 | — | — | CN | disclosed |
| CN-111826355-A | Scopolia acutangula P450 enzyme and application thereof in preparation of tropinone | 中国科学院分子植物科学卓越创新中心 | 2020-10-27 | — | — | CN | disclosed |
| CN-111826355-A | Scopolia acutangula P450 enzyme and application thereof in preparation of tropinone | 中国科学院分子植物科学卓越创新中心 | 2020-10-27 | — | — | CN | disclosed |