Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 6/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24476668 | 0.84 | CYP3A4 (0.66) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL6873042 | 0.81 | PGR (0.72) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL2835215 | 0.81 | PGR (0.72) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL23805202 | 0.81 | PGR (0.72) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL6245967 | 0.81 | PGR (0.72) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL23822244 | 0.77 | PGR (0.54) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL24476271 | 0.77 | PGR (0.54) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL24476431 | 0.77 | PGR (0.54) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL24476268 | 0.77 | PGR (0.54) | PGRCYP2C19ESR1NR3C1SLC6A4 | |
| SCHEMBL5974963 | 0.77 | PGR (0.54) | PGRCYP2C19ESR1NR3C1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169672-A1 | COMPOUNDS FOR TARGETED THERAPIES OF CASTRATION RESISTANT PROSTATE CANCER | PURDUE RESEARCH FOUNDATION | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169672-A1 | COMPOUNDS FOR TARGETED THERAPIES OF CASTRATION RESISTANT PROSTATE CANCER | KLK3, AR, ACP3 | PGR 777/4885CYP2C19 3711/4885ESR1 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.