SCHEMBL24477553

SCHEMBL24477553

CC1CCC(F)(F)CC1(C)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24477623 0.77
SCHEMBL14681561 0.77
SCHEMBL12446358 0.77
SCHEMBL24477677 0.76 ALDH1A1 (0.31) ALDH1A1LMNATHRBALOX15MAPK1
SCHEMBL15728043 0.76
SCHEMBL24477552 0.76 ALDH1A1 (0.31) ALDH1A1LMNATHRBALOX15MAPK1
SCHEMBL27867973 0.75
SCHEMBL15728045 0.73
SCHEMBL10687403 0.68 ALDH1A1 (0.32) ALDH1A1LMNATHRBALOX15MAPK1
SCHEMBL16386235 0.67 ALDH1A1 (0.31) ALDH1A1LMNATHRBALOX15MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022111621-A1 AMINOHETEROARYL KINASE INHIBITORS ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) 2022-06-02 WO disclosed