Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.67 |
| ▸ | CA1 | P00915 | 4/20 | 0.67 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.51 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468343 | 0.88 | CA2 (0.77) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL8950290 | 0.88 | CA2 (0.83) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL27712453 | 0.87 | CA2 (0.59) | CA2CA1CPB2ZDHHC7DPP7 | |
| SCHEMBL672594 | 0.86 | CA2 (0.74) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL3682239 | 0.86 | CA2 (0.74) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL29152695 | 0.86 | CA2 (0.74) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL3682221 | 0.86 | CA2 (0.74) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL3677110 | 0.86 | CA2 (0.74) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL28254433 | 0.86 | CA2 (0.74) | CA2CA1ZDHHC7BIRC2MAPK1 | |
| SCHEMBL21052368 | 0.86 | CA2 (0.80) | CA2CA1ZDHHC7BIRC2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169639-A1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169639-A1 | N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION | HAVCR2, NR0B1, CYP7A1 | CA2 4658/4885CA1 3993/4885CPB2 536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.