Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA7 | P43166 | 3/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8055346 | 0.92 | CA12 (0.44) | CA12CA7CA14JAK2JAK1 | |
| SCHEMBL10280119 | 0.81 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL12385865 | 0.81 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL24773688 | 0.81 | CA12 (0.55) | CA12CA7CA14JAK2JAK1 | |
| SCHEMBL15552592 | 0.81 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL13580619 | 0.80 | CA12 (0.36) | CA12CA7CA14JAK2JAK1 | |
| SCHEMBL15996338 | 0.75 | CA12 (0.44) | CA12CA7CA14JAK2JAK1 | |
| SCHEMBL17778087 | 0.75 | CA12 (0.44) | CA12CA7CA14JAK2JAK1 | |
| SCHEMBL8263013 | 0.74 | CA12 (0.48) | CA12CA7CA14JAK1CA9 | |
| SCHEMBL15214569 | 0.74 | CA12 (0.48) | CA12CA7CA14JAK1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111621-A1 | AMINOHETEROARYL KINASE INHIBITORS | ANRUI BIOMEDICAL TECHNOLOGY (GUANGZHOU) CO., LTD. (CN) | 2022-06-02 | — | — | WO | disclosed |