Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KHK | P50053 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1543398 | 0.84 | HRH3 (0.40) | KMT2AHRH3KCNH2MEN1TFPI2 | |
| SCHEMBL24582089 | 0.83 | KMT2A (0.43) | KMT2AHPGDSMN1; SMN2L3MBTL3L3MBTL1 | |
| SCHEMBL3159987 | 0.82 | HTR6 (0.41) | KMT2AHPGDSMN1; SMN2L3MBTL3L3MBTL1 | |
| SCHEMBL5429121 | 0.80 | MEN1 (0.41) | KMT2AHRH3KCNH2MEN1 | |
| SCHEMBL3083396 | 0.80 | MEN1 (0.44) | KMT2AL3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL2554838 | 0.79 | KMT2A (0.44) | KMT2AHPGDSMN1; SMN2L3MBTL3L3MBTL1 | |
| SCHEMBL13632342 | 0.78 | MEN1 (0.43) | KMT2AHRH3KCNH2MEN1 | |
| SCHEMBL5016034 | 0.78 | MEN1 (0.43) | KMT2AL3MBTL3L3MBTL1HRH3KCNH2 | |
| SCHEMBL2318967 | 0.78 | MEN1 (0.43) | KMT2AHRH3KCNH2MEN1 | |
| SCHEMBL13632346 | 0.78 | MEN1 (0.43) | KMT2AHRH3KCNH2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |