Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.66 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24480913 | 0.92 | GPR119 (0.56) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL22119507 | 0.90 | DDB1 (0.59) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL25634142 | 0.89 | DDB1 (0.54) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL25631758 | 0.88 | DDB1 (0.53) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL24671737 | 0.86 | DDB1 (0.54) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL27161752 | 0.86 | DDB1 (0.54) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL22119552 | 0.86 | DDB1 (0.57) | GPR119DDB1CRBNMAPT | |
| SCHEMBL25631762 | 0.85 | DDB1 (0.51) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL27039385 | 0.84 | PTPN2 (0.65) | GPR119DDB1CRBNALDH1A1LMNA | |
| SCHEMBL23120993 | 0.84 | GPR119 (0.54) | GPR119DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529248-A | Benzene ring derivative, composition and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |