Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 16/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.39 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462926 | 0.94 | CRBN (0.48) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL22873398 | 0.88 | CRBN (0.54) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL24671135 | 0.84 | CRBN (0.48) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL30985067 | 0.83 | CRBN (0.51) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL24480490 | 0.82 | CRBN (0.70) | CRBNDDB1IKZF2ARALDH1A1 | |
| SCHEMBL24389292 | 0.81 | CRBN (0.51) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL20233690 | 0.80 | CRBN (0.54) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL22873430 | 0.79 | CRBN (0.48) | CRBNDDB1ARALDH1A1CHRM2 | |
| SCHEMBL21480820 | 0.79 | CRBN (0.50) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL27344039 | 0.79 | CRBN (0.50) | CRBNDDB1ARALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |