Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984834 | 0.92 | CRBN (0.51) | CRBNESR1DDB1IKZF3ALDH1A1 | |
| SCHEMBL25133215 | 0.92 | CRBN (0.51) | CRBNESR1DDB1IKZF3ALDH1A1 | |
| SCHEMBL22873430 | 0.89 | CRBN (0.48) | CRBNESR1DDB1IKZF3ALDH1A1 | |
| SCHEMBL22873398 | 0.89 | CRBN (0.54) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL24389292 | 0.86 | CRBN (0.51) | CRBNESR1DDB1IKZF3ALDH1A1 | |
| SCHEMBL21480820 | 0.85 | CRBN (0.50) | CRBNESR1DDB1IKZF3ALDH1A1 | |
| SCHEMBL24671135 | 0.83 | CRBN (0.48) | CRBNESR1DDB1IKZF3ALDH1A1 | |
| SCHEMBL27462926 | 0.83 | CRBN (0.48) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL27344039 | 0.83 | CRBN (0.50) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL24480495 | 0.83 | CRBN (0.46) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146502-A1 | WEE1 DEGRADING COMPOUNDS | BEIJING NEOX BIOTECH LIMITED (CN) | 2024-07-11 | — | — | WO | disclosed |