Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24481222 | 0.95 | KDM4E (0.41) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL27162825 | 0.91 | KDM4E (0.42) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL24480292 | 0.91 | HPGD (0.46) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL412749 | 0.90 | HPGD (0.47) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL24481256 | 0.89 | CNR1 (0.41) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL2165760 | 0.88 | HPGD (0.50) | KDM4EHPGDRECQLEPHX1MAPT | |
| Hydrochloric Acid SCHEMBL3962545 | 0.87 | HPGD (0.49) | KDM4EHPGDRECQLEPHX1MAPT | |
| Hydrochloric Acid SCHEMBL3278700 | 0.87 | HPGD (0.49) | KDM4EHPGDRECQLEPHX1MAPT | |
| SCHEMBL3279038 | 0.86 | HPGD (0.46) | KDM4EPKMHPGDRECQLEPHX1 | |
| SCHEMBL24480524 | 0.85 | HTR4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425646-A | Phosphono derivative, composition thereof and pharmaceutical application thereof | 西藏海思科制药有限公司 | 2024-01-19 | — | — | CN | disclosed |
| CN-116529248-A | Benzene ring derivative, composition and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-08-01 | — | — | CN | disclosed |
| WO-2022228547-A1 | PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-11-03 | — | — | WO | disclosed |
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |
| WO-2022111526-A1 | BENZENE RING DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | disclosed |