Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | CCR5 | P51681 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.45 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088636 | 0.85 | CCR1 (0.52) | CCR1CCR5RAB9ACYP1A2CCR8 | |
| SCHEMBL24619705 | 0.83 | CCR1 (0.43) | CCR1CCR5RAB9ACYP1A2CCR8 | |
| SCHEMBL2119571 | 0.80 | CCR1 (0.46) | CCR1CCR5RAB9ACYP1A2CCR8 | |
| SCHEMBL2119502 | 0.80 | CCR1 (0.46) | CCR1CCR5RAB9ACYP1A2METAP2 | |
| SCHEMBL24207564 | 0.80 | KDM4E (0.48) | CCR1CCR5RAB9ACYP1A2CCR8 | |
| SCHEMBL24482788 | 0.80 | CCR1 (0.46) | CCR1CCR5RAB9ACYP1A2CCR8 | |
| SCHEMBL22509683 | 0.80 | BACE1 (0.48) | CCR1CCR5RAB9ACYP1A2CCR8 | |
| SCHEMBL24619702 | 0.80 | CCR1 (0.41) | CCR1CCR5CYP1A2CCR8CYP2A6 | |
| SCHEMBL24619662 | 0.80 | CCR1 (0.41) | CCR1CCR5CYP1A2CCR8CYP2A6 | |
| SCHEMBL11804743 | 0.78 | CCR1 (0.54) | CCR1CCR5RAB9ACYP1A2CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |