Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.33 |
| ▸ | SELL | P14151 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
| ▸ | SELE | P16581 | 1/20 | 0.33 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963774 | 0.82 | ALDH1A1 (0.34) | KDM4ECYP1A2CYP2A6TDP1ALDH1A1 | |
| SCHEMBL24482811 | 0.80 | CCR1 (0.50) | CCR1CCR5CCR8KDM4ECYP1A2 | |
| SCHEMBL24619705 | 0.80 | CCR1 (0.43) | CCR1CCR5CCR8KDM4ECYP1A2 | |
| SCHEMBL25251144 | 0.77 | DGAT1 (0.35) | KDM4ECYP2A6TDP1ALDH1A1 | |
| SCHEMBL9088995 | 0.77 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ECYP1A2 | |
| SCHEMBL22509683 | 0.77 | BACE1 (0.48) | CCR1CCR5CCR8KDM4ECYP1A2 | |
| SCHEMBL24619662 | 0.77 | CCR1 (0.41) | CCR1CCR5CCR8KDM4ECYP1A2 | |
| SCHEMBL20047641 | 0.74 | NOS3 (0.39) | CCR1CCR5CCR8CYP1A2CYP2A6 | |
| SCHEMBL1964184 | 0.73 | PDE10A (0.30) | — | |
| SCHEMBL1289578 | 0.72 | LMNA (0.40) | KDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |