Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058173 | 0.74 | TP53 (0.33) | TSHRTP53 | |
| SCHEMBL8465943 | 0.74 | TP53 (0.33) | TSHRTP53 | |
| SCHEMBL14495737 | 0.74 | TSHR (0.36) | TSHRTP53ALOX15LMNA | |
| SCHEMBL1270359 | 0.69 | TSHR (0.41) | TSHRTP53ALOX15LMNA | |
| SCHEMBL22510064 | 0.69 | MEN1 (0.33) | TSHRLMNA | |
| SCHEMBL12166805 | 0.67 | TP53 (0.34) | TSHRTP53 | |
| Acetic Acid SCHEMBL7135968 | 0.65 | CA1 (0.37) | TSHRTP53LMNA | |
| SCHEMBL15754905 | 0.65 | TP53 (0.36) | TSHRTP53ALOX15LMNA | |
| SCHEMBL26225124 | 0.65 | TSHR (0.37) | TSHRTP53ALOX15LMNA | |
| SCHEMBL14495576 | 0.64 | TSHR (0.39) | TSHRTP53ALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220169580-A1 | METHODS OF CARBON-CARBON BOND FRAGMENTATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220169580-A1 | METHODS OF CARBON-CARBON BOND FRAGMENTATION | CYCS, COX6C, COXFA4L2 | TSHR 4604/4885TP53 369/4885ALOX15 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.