Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 5/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | GLP1R | P43220 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16221915 | 1.00 | CASP2 (0.56) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL24155207 | 1.00 | CASP2 (0.56) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL15759326 | 1.00 | CASP2 (0.56) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL20255020 | 0.99 | CASP2 (0.54) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL25962907 | 0.98 | CASP2 (0.53) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL16217752 | 0.98 | CASP2 (0.53) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL23839867 | 0.97 | CASP2 (0.53) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL23849342 | 0.97 | CASP2 (0.53) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL20254831 | 0.97 | CASP2 (0.53) | CASP2FAAHNAAADNM1NOD1 | |
| SCHEMBL8210240 | 0.91 | CASP2 (0.59) | CASP2FAAHNAAADNM1NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022115799-A1 | RADIOPHARMACEUTICAL CONJUGATES TARGETING GUANYLYL CYCLASE C, AND COMPOSITIONS AND USES THEREOF | RAYZEBIO, INC. (US) | 2022-06-02 | — | — | WO | disclosed |