Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 4/20 | 0.53 |
| ▸ | BDNF | P23560 | 3/20 | 0.53 |
| ▸ | PTN | P21246 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LGALS3 | P17931 | 4/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.47 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.47 |
| ▸ | CD69 | Q07108 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.41 |
| ▸ | FGF1 | P05230 | 2/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | FGF2 | P09038 | 1/20 | 0.40 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341681 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL31556472 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL29459917 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL31067715 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL31067693 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL932879 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL6748051 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL20516492 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL22071113 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 | |
| SCHEMBL29459916 | 1.00 | MDK (0.53) | MDKBDNFPTNMAPK1LGALS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | CHORDA PHARMA, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | CHORDA PHARMA, INC. | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11773055-B2 | Chemical derivatives and methods for synthesizing and compounding chemical derivatives related to capsaicin palmitate and capsaicin prodrugs | HCAR2, HCAR3, TRPV1 | MDK 3892/4885BDNF 712/4885PTN 4392/4885 |
| US-20220168259-A1 | CHEMICAL DERIVATIVES AND METHODS FOR SYNTHESIZING AND COMPOUNDING CHEMICAL DERIVATIVES RELATED TO CAPSAICIN PALMITATE AND CAPSAICIN PRODRUGS | HCAR2, HCAR3, TRPV1 | MDK 3892/4885BDNF 712/4885PTN 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.