Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.72 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.72 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.72 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.72 |
| ▸ | HRH1 | P35367 | 2/20 | 0.72 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.72 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.72 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.72 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859538 | 0.97 | CHRM2 (0.66) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| Cadaverine Tartrate SCHEMBL2528604 | 0.89 | CHRM2 (0.74) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| Cadaverine Tartrate SCHEMBL2528602 | 0.89 | CHRM2 (0.74) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL725535 | 0.89 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL13175653 | 0.89 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL14709412 | 0.89 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL574530 | 0.88 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL4879639 | 0.88 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL9111155 | 0.87 | CHRM2 (0.64) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| Hydrochloric Acid SCHEMBL4771342 | 0.87 | CHRM2 (0.66) | CHRM2CHRM1CHRM3CHRM5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1880718-B1 | Pharmaceutical preparation for oral administration with controlled drug release in the small intestine colon and process of prepartion thereof | PFLEGER R CHEM FAB (DE) | 2011-09-21 | — | — | EP | claimed |