Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.66 |
| ▸ | HRH1 | P35367 | 2/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.66 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.66 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.66 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | HRH2 | P25021 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2448532 | 0.97 | CHRM2 (0.72) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL13175653 | 0.92 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL725535 | 0.92 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL14709412 | 0.92 | CHRM2 (0.77) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL574530 | 0.91 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL4879639 | 0.91 | CHRM2 (0.67) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| Hydrochloric Acid SCHEMBL4771342 | 0.90 | CHRM2 (0.66) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL9107429 | 0.88 | CHRM2 (0.64) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| SCHEMBL9111155 | 0.88 | CHRM2 (0.64) | CHRM2CHRM1CHRM3CHRM5HRH1 | |
| Fumaric Acid SCHEMBL14696873 | 0.87 | CHRM2 (0.70) | CHRM2CHRM1CHRM3CHRM5HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358399-B2 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propaneamine | CHEMI SPA (IT) | 2008-04-15 | — | — | US | disclosed |
| US-20060079716-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propaneamine | CHEMI SPA (IT) | 2006-04-13 | — | — | US | disclosed |
| US-20030144352-A1 | Antimuscarinic aerosol | PHARMACIA & UPJOHN COMPANY | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144352-A1 | Antimuscarinic aerosol | CHRM3, CHRM1, CHRM5 | CHRM2 4/4885CHRM1 2/4885CHRM3 1/4885 |
| US-20060079716-A1 | Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenyl-propaneamine | PNMT, INMT, DRD4 | CHRM2 169/4885CHRM1 182/4885CHRM3 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.