Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC26A4 | O43511 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629713 | 1.00 | SLC26A4 (0.48) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL24485356 | 0.97 | SLC26A4 (0.49) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL29630182 | 0.97 | SLC26A4 (0.49) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL29629763 | 0.94 | SLC26A4 (0.47) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL24484914 | 0.94 | SLC26A4 (0.47) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL24485642 | 0.93 | SLC26A4 (0.48) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL29630118 | 0.93 | SLC26A4 (0.48) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL24485644 | 0.91 | SLC26A4 (0.46) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL29630097 | 0.91 | SLC26A4 (0.46) | SLC26A4KMT2AMAPTMEN1TSHR | |
| SCHEMBL24485706 | 0.90 | SLC26A4 (0.49) | SLC26A4KMT2AMAPTMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022112352-A1 | HETEROCYCLE DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |