Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752478 | 0.75 | GPR84 (0.47) | GPR84ALDH1A1PKMHPGD | |
| SCHEMBL31282637 | 0.75 | GPR84 (0.47) | GPR84ALDH1A1PKMHPGD | |
| SCHEMBL11145768 | 0.75 | GPR84 (0.47) | GPR84ALDH1A1PKMHPGD | |
| SCHEMBL31282520 | 0.75 | GPR84 (0.47) | GPR84ALDH1A1PKMHPGD | |
| SCHEMBL27667717 | 0.75 | GPR84 (0.47) | GPR84ALDH1A1PKMHPGD | |
| SCHEMBL28171528 | 0.75 | GPR84 (0.47) | GPR84ALDH1A1PKMHPGD | |
| Hydrochloric Acid SCHEMBL31210324 | 0.74 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGD | |
| Hydrochloric Acid SCHEMBL31210323 | 0.74 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGD | |
| Hydrochloric Acid SCHEMBL29740767 | 0.74 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGD | |
| Hydrochloric Acid SCHEMBL31210325 | 0.74 | GPR84 (0.46) | GPR84ALDH1A1PKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352340-B2 | Pyridine and pyridimine compounds as PI3K-gamma inhibitors | INCYTE CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352340-B2 | Pyridine and pyridimine compounds as PI3K-gamma inhibitors | PIK3CG, PIK3CD, PIK3CB | GPR84 2194/4885ALDH1A1 2997/4885PKM 887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.