⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24487658 | 0.81 | — | — | |
| SCHEMBL1324927 | 0.81 | — | — | |
| SCHEMBL21994193 | 0.81 | — | — | |
| SCHEMBL6565675 | 0.81 | — | — | |
| SCHEMBL20022627 | 0.73 | ALDH1A1 (0.36) | — | |
| SCHEMBL22257204 | 0.71 | — | — | |
| SCHEMBL14730402 | 0.71 | — | — | |
| SCHEMBL5160595 | 0.71 | — | — | |
| SCHEMBL14462887 | 0.71 | — | — | |
| SCHEMBL3593914 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352351-B2 | Compounds and methods for the targeted degradation of androgen receptor | ARVINAS OPERATIONS, INC. (US) | 2022-06-07 | — | — | US | disclosed |