SCHEMBL244868

SCHEMBL244868

Clc1cc2ccccc2nc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
ALDH1A1 P00352 5/20 0.56
GLA P06280 3/20 0.56
HPGD P15428 3/20 0.56
MAPT P10636 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
ACHE P22303 1/20 0.56
KDM4E B2RXH2 6/20 0.47
PKM P14618 2/20 0.45
LMNA P02545 2/20 0.45
EGFR P00533 1/20 0.44
TOP2A P11388 1/20 0.44
TOP2B Q02880 1/20 0.44
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
NQO2 P16083 1/20 0.42
GAA P10253 2/20 0.42
HTR3A P46098 1/20 0.42
STAT3 P40763 1/20 0.42
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29911341 1.00 KMT2A (0.59) KMT2AALDH1A1GLAHPGDMAPT
SCHEMBL31278632 0.98 KMT2A (0.57) KMT2AALDH1A1GLAHPGDMAPT
Quinoxaline SCHEMBL28427327 0.90 KMT2A (0.50) KMT2AALDH1A1GLAHPGDMAPT
Toluene SCHEMBL28155976 0.88 KMT2A (0.49) KMT2AALDH1A1GLAHPGDMAPT
Phosphoric Acid SCHEMBL27955583 0.88 KMT2A (0.49) KMT2AALDH1A1GLAHPGDMAPT
SCHEMBL17993629 0.79 KMT2A (0.57) KMT2AALDH1A1GLAHPGDMAPT
SCHEMBL1067857 0.77 KDM4E (0.59) KMT2AALDH1A1GLAHPGDMAPT
SCHEMBL2729303 0.77 KMT2A (0.55) KMT2AALDH1A1GLAHPGDMAPT
SCHEMBL1467074 0.77 ALDH1A1 (0.59) KMT2AALDH1A1GLAHPGDMAPT
SCHEMBL1767846 0.77 KMT2A (0.55) KMT2AALDH1A1GLAHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 680 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025124444-A1 USE OF HYDROXYPROLINE AND DERIVATIVE THEREOF, BIOLOGICAL HERBICIDE, BROAD-SPECTRUM HERBICIDE, AND WEED CONTROL METHOD 三亚市国家耐盐碱水稻技术创新中心 2025-06-19 WO claimed
CN-115232115-B Quinclorac-oxazoline chiral ligand and preparation method and application thereof 贵州大学 2024-04-16 CN claimed
CN-116660424-A Method for detecting quinclorac in honey 秦皇岛海关技术中心 2023-08-29 CN claimed
CN-112225697-B Preparation method of enantiomer pure chloroquine and chloroquine phosphate 宁波大学 2023-01-03 CN claimed
CN-115232115-A Quinclorazoline-quinazoline chiral ligand as well as preparation method and application thereof 贵州大学 2022-10-25 CN claimed
CN-113854071-A Green planting method of alpine dry rice and green alpine dry rice 周佩杰 2021-12-31 CN claimed
CN-113845475-A Method for preparing hydroxychloroquine sulfate by using microchannel reaction device 南京先进生物材料与过程装备研究院有限公司 2021-12-28 CN claimed
CN-109776406-B Method for cross coupling of ether compound and quinoline derivative 湘潭大学 2021-05-04 CN claimed
CN-111286315-A Compound oil-displacing agent for increasing recovery ratio of low-permeability reservoir and preparation method thereof 东野升富 2020-06-16 CN claimed
CN-110495464-A A kind of Herbicidal combinations of the humulone containing dichloroquinoline and its application ANHUI SHANGHE WODA BIOTECHNOLOGY CO LTD 2019-11-26 CN claimed
EP-0925282-A1 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY DOWELANCO (US) 1999-06-30 EP claimed
WO-1998039966-A1 NITROGEN-CONTAINING OXYALKYLENE ESTERS AND USES THEREOF BAR-ILAN UNIVERSITY (IL) 1998-09-17 WO claimed
WO-1998005645-A9 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY 1998-08-20 WO claimed
CN-1188481-A Transition metal catalysts based on bidentate ligands containing pyridine or quinoline moieties LEONDELL CHEMICAL CORP (US) 1998-07-22 CN claimed
WO-1998005645-A1 4-SUBSTITUTED QUINOLINE DERIVATIVES HAVING FUNGICIDAL ACTIVITY DOW AGROSCIENCES LLC (US) 1998-02-12 WO claimed
CN-1134424-A Synthesis process of 2,3-disubstituted oxaziridine YAN ZIMENG (CN) 1996-10-30 CN claimed
US-4795621-A CATALYST OF QUINOLINE COMPOUND AND METAL COMPOUND SHIN NISSO KAKO CO., LTD. (JP) 1989-01-03 US claimed
US-4632696-A POSTEMERGENCE, PREEMERGENCE APPLICATIONS BASF AKTIENGESELLSCHAFT (DE) 1986-12-30 US claimed
US-4497651-A Dichloroquinoline derivatives for use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1985-02-05 US claimed
EP-0060429-B1 DICHLOROQUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1984-01-25 EP claimed