SCHEMBL2448745

SCHEMBL2448745

CCCC(CCC)(CCC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
FDPS P14324 2/20 0.36
ALDH1A1 P00352 3/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
THRB P10828 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29025723 0.97 KDM4C (0.37) FFAR3HDAC1HDAC2HDAC3HDAC8
SCHEMBL9179083 0.97 KDM4C (0.37) FFAR3HDAC1HDAC2HDAC3HDAC8
SCHEMBL9181232 0.92 ALDH1A1 (0.35) FFAR3HDAC1HDAC2HDAC3HDAC8
SCHEMBL9181183 0.92 CYP4F2 (0.36) FFAR3HDAC1HDAC2HDAC3HDAC8
SCHEMBL2136858 0.89 AKR1B1 (0.39) FDPSALDH1A1MEN1KMT2ATSHR
SCHEMBL9184201 0.89 ALDH1A1 (0.35) FFAR3HDAC1HDAC2HDAC3HDAC8
SCHEMBL2347926 0.89 AKR1B1 (0.39) FDPSALDH1A1MEN1KMT2ATSHR
SCHEMBL5164573 0.89 KDM4C (0.33) FFAR3HDAC1HDAC2HDAC3HDAC8
SCHEMBL9181624 0.89 ALDH1A1 (0.35) FFAR3HDAC1HDAC2HDAC3HDAC8
SCHEMBL9180694 0.89 TDP1 (0.39) ALDH1A1MEN1KMT2ATSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184508-A Method for preparing valproic acid by diethyl malonate method 湖南省湘中制药有限公司 2024-06-14 CN claimed
CN-118010875-A Detection method for impurities in valproic acid prepared by diethyl malonate method 湖南省湘中制药有限公司 2024-05-10 CN claimed
CN-116874347-B Preparation method of impurity dipropylvaleric acid in valproic acid process 湖南省湘中制药有限公司 2024-03-29 CN claimed
CN-116874347-A Preparation method of impurity dipropylvaleric acid in valproic acid process 湖南省湘中制药有限公司 2023-10-13 CN claimed
CN-114646698-B Method for detecting sodium valproate and related substances thereof in sodium valproate injection 西安远大德天药业股份有限公司 2023-09-22 CN claimed
CN-116143658-A Method for simultaneously preparing tripropylacetonitrile, tripropylamide and tripropylacetic acid 上海青平药业有限公司 2023-05-23 CN claimed
CN-114646698-A Method for detecting sodium valproate and related substances thereof in sodium valproate injection 西安远大德天药业股份有限公司 2022-06-21 CN claimed
CN-110204695-B Narrow-band receptor type conjugated polymer containing low polyethylene glycol side chain structure and preparation method and application thereof 吉林大学 2021-02-26 CN claimed
CN-110204695-A A kind of narrowband system receptor type conjugated polymer containing oligoethylene glycol side-chain structure and preparation method thereof, application 吉林大学 2019-09-06 CN claimed
CN-104419326-A Slurry composition for chemical mechanical polishing COWON INNOTECH INC 2015-03-18 CN claimed
CN-1260003-C Silica gel continuous bar and preparation process thereof YANG GENGLIANG (CN) 2006-06-21 CN claimed
CN-1483510-A Silica gel continuous bar and preparation process thereof 杨更亮 2004-03-24 CN claimed
US-5117022-A Antitumor THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1992-05-26 US claimed
WO-1990002131-A1 HYDROPHOBIC CIS-PLATINUM COMPLEXES EFFICIENTLY INCORPORATED INTO LIPOSOMES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1990-03-08 WO claimed
US-3958011-A ADMINISTERING LABAZ (FR) 1976-05-18 US claimed
CN-118373735-B Valproic acid prepared by cyanoacetic acid ester method 湖南省湘中制药有限公司 2025-02-21 CN disclosed
CN-118388335-A Method for controlling impurities in valproic acid 湖南省湘中制药有限公司 2024-07-26 CN disclosed
US-3958011-A ADMINISTERING LABAZ (FR) 1976-05-18 US disclosed
US-3958011-A ADMINISTERING LABAZ (FR) 1976-05-18 US disclosed
US-3958011-A ADMINISTERING LABAZ (FR) 1976-05-18 US disclosed